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Dual Extraction

Extracting a mushroom twice, once with hot water and once with alcohol, so both water-soluble and alcohol-soluble compounds end up in the final product.

Also called dual-extracted · double extraction

On the Evidence Gradient

IEstablished mechanismsIIMixed evidenceIIITheoretical biophysicsIVExperiential wellness art
  • Tier IWater draws out polysaccharides such as beta-glucans; alcohol draws out triterpenes and other compounds that dissolve poorly in water.
  • Tier IIIA dual extract delivers more of a mushroom's benefits than a single extract. Reasonable from the chemistry, not yet compared in human studies.

Tiers rate claims, not devices. How the Evidence Gradient works

Dual extraction is a way of making a mushroom extract in two stages so it carries both major families of compounds. Hot water draws out the polysaccharides, including beta-glucans. Alcohol draws out the triterpenes and other compounds that dissolve poorly in water. The two extracts are then combined.

Why Two Solvents

Different compounds dissolve in different liquids. In reishi, polysaccharides and triterpenes are the two main groups of active compounds; hot water is the traditional way to extract the polysaccharides, and ethanol is the traditional way to extract the triterpenes (Zheng et al., 2020). Using one solvent alone favors one family of compounds over the other, so dual extraction uses both.

How We Use It

Ozark Forest Elixir is dual extracted so each dropper carries both the water-soluble and the alcohol-soluble parts of its wildcrafted mushrooms.

What Is Still Open

The chemistry behind dual extraction is sound. Whether a dual extract produces greater effects in people than a single extract has not been tested directly in human studies.

References

Zheng, S., Zhang, W., & Liu, S. (2020). Optimization of ultrasonic-assisted extraction of polysaccharides and triterpenoids from the medicinal mushroom Ganoderma lucidum and evaluation of their in vitro antioxidant capacities. PLoS ONE, 15(12), Article e0244749. https://doi.org/10.1371/journal.pone.0244749

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